Blog

Linked Clinical Trials initiative gathers momentum

We now have linked clinical trials deposits coming in from five publishers: BioMedCentral, BMJ, Elsevier, National Institute for Health Research and PLOS. It’s still a relatively small pool of metadata - around 4000 DOIs with associated clinical trial numbers - but we’re delighted to see that “threads” of publications are already starting to form. If you look at this article in The Lancet and click on the Crossmark button you will see that in the Clinical Trials section there are links to three other articles reporting on the same trial: two from the American Heart Journal and one from BMJ’s Heart.

Clinical trial data and articles linked for the first time

It’s here. After years of hard work and with a huge cast of characters involved, I am delighted to announce that you will now be able to instantly link to all published articles related to an individual clinical trial through the Crossmark dialogue box. Linked Clinical Trials are here! In practice, this means that anyone reading an article will be able to pull a list of both clinical trials relating to that article and all other articles related to those clinical trials – be it the protocol, statistical analysis plan, results articles or others – all at the click of a button.

Linking clinical trials = enriched metadata and increased transparency

We will shortly be adding a new feature to Crossmark. In a section called “Clinical Trials” we will be using new metadata fields to link together all of the publications we know about that reference a particular clinical trial. Most medical journals make clinical trial registration a prerequisite for publication. Trials should be registered with one of the fifteen WHO-approved public trial registries , or with clinicaltrials.gov which is run by the US National Library of Medicine.